Crypt of the Ancients is one of the overall best farming areas in the game, and in my opinion the best mp10 farming area for Demon Hunters.
(Will make a better video at some point)
33 runs in an hour at 4x speed:
Start on the act 1 quest The Broken Blade: Talk to Aleric. Run to Festering Woods, enter Crypt of the Ancients. You will get it as checkpoint and can teleport there directly.
Begin by gathering up the mobs and try to fight with as many summoners in range as possible so that they keep summoning more skeletons. If they are too spread out, you can kite between the groups. This helps you survive by giving you more targets to leech, proc night stalker and get globes from. But more importantly, you get more loot/exp. Don't bother with the casters or the last remaining skeletons, it's not worth it. I can recommend Tianzi's video for more detailed info (link at the end), my videos can probably be of a little use too.
Disable loot text automatically showing, it's fun at first but will get you killed.
Clear some inventory space for all the epic loot you will find ;)
This is the stem of the build. It's the synergy between these skills that make it work, at least for me.
This is the one I favor. It's the offensively strongest version, mostly thanks to the extra hatred. Shuriken procs both mortal enemy and night stalker which makes it stronger than it looks. However there are many other viable alternatives.
Imminent Doom for dps.
Highest damage, my choice. The delay is not so bad when you can instantly get life steal from Jagged Spikes.
Stun. Not tested but some people say it's good, mostly calamity users
Bitter pill for more disc.
Personally I don't need it, but could be good.
Usable, the best skill for procing.
I do not recommend Volatile Explosion, kills trash faster which isn't needed, and doesn't add anything else. It has half the proc chance of the other runes. Can cause permanent damage to your eyes.
Spike Trap with Echoing Blast:
Our strongest hatred spender. Skeletons are slow moving melee units with a very simple "attack the player"-AI, which is perfect for this skill.
Shadow Power with Gloom:
No explanation needed.
Caltrops with Jagged Spikes:
You can have up to 5 of these out. With Custom Engineering they last 12 seconds and do 540% damage. If you cast it during Gloom it will snapshot the life steal, which improves your survivability a lot, especially when afflicted by freeze and such. For the same reasons as with Echoing Blast, CotA is the perfect area to use this in.
Note: Does not profit from attack speed, but crits even if you can't see it.
Last 2 active skills is your choice:
Vault with Trail of Cinders or Tumble
You often get trapped in narrow passages or the hordes of skeletons. I recommend most players to use this, at least to begin with.
Marked for Death with Mortal Enemy
More dps against the skeleton champion, which is what you should focus on increasing your dps against. Mortal enemy gives hatred, which also increases your dps. It can proc every 0.5 seconds from Chain of Torment and Shuriken Cloud.
Chakram with Shuriken Cloud
If you cast it with Gloom on, it will keep the life leech for the full duration. It procs Night Stalker and Mortal Enemy. A bit extra dps. Not affected by attack speed.
Sentry with Guardian Turret
Some extra protection.
Sentry with Chain of Torment
For the damage, life steal and Mortal Enemy proc. With 3 out it can give you up to +18 hatred per second. However, it's awkward to use, requires positioning and costs hatred. Most people dislike it. I find it fun to use once in a while. Do not use it with nat's helm!
Rain of Vengeance
Some people like it, I'm not sure.
If you need more discipline.
Works great thanks to the heavy mob density, even with low aps. Very high disc and preparation is a possible alternative, but not a good one.
For once it works well on mp10, thanks again to the hordes of skeletons. The DH generally has good dps on low mps but it decreases on higher since we run out of hatred. This build and area is an exception, thanks to being able to use this skill.
Takes Jagged Spikes and doubles it ^_^. You also need it for Echoing blast since you have a lot of hatred to spend, without this it goes to waste. I've seen some calamity users run archery instead, but I don't get how you manage to use up your hatred without it.
Regular high mp stuff. You don't need much +disc but a little extra is nice. Stone of Jordan with Spike Trap or Bola Shot bonus is the best ring choice, with this build spike trap is likely best.
The only absolutely necessary stat is at least 5-7 pickup radius.
You could do this with a 100m build, if you buy the right items:
Weapon: Manticore with high crit, dex, 1 socket 1300 dps. The last affix isn't important, maybe you can get a bit of vit or extra dex.
Quiver: Dead Man's Legacy with Bola Shot bonus and a useful random roll like dex, vit, socket, life%.
Ring1: Stone of Jordan with Spike Trap or Bola Shot.
Ring2: Hellfire, rare or Litany of the Undaunted. First priority id dex, chc, chd.
Bracers: Craft. Good place to get pickup radius.
Shoulders: Craft (or vile ward). Good place to get pickup radius.
Boots: Nats with vit.
Chest: Nats with spike trap bonus. Vit, dex, armor, all resist, damage taken from elites. Find what you can afford. Remember that a good skill bonus is worth more than a few stat points.
Belt: Inna's with all resist or dex+vit
Pants: Inna's with all resist or vit
Helm: Mempo with vitality.
Shouldn't cost much, unless you don't craft. Bidding is much cheaper than buyouts, unless you're very lucky or patient. You'll probably have a bit too much defensive and not enough offensive with my suggested items, but you can adjust that. This is just an example, and should only be followed exactly if you're completely lost :)
Nice stats to reach would be 50k life, 400 all res, 200k dps.
Based on Tianzi's monk guide which I got the inspiration for the build and play style from.